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CIT kinase phosphorylation as significant regulatory node for cellular checkpoints

IntroductionCitron Rho-interacting serine/threonine kinase (CIT) is a major cytosolic protein kinase essential for midbody organisation, abscission, and cytokinesis. Dysregulation and mutations in CIT are associated with multiple cancers and neurodevelopmental disorders, including microcephaly. Alth...

Deskribapen osoa

Gorde:
Egile Nagusiak: Jaytha Thomas, Fathimathul Lubaba, Mukhtar Ahmed, Althaf Mahin, Levin John, Athira Perunelly Gopalakrishnan, Suhail Subair, Prathik Basthikoppa Shivamurthy, Rajesh Raju, Sowmya Soman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2026-01-01
Saila:Frontiers in Bioinformatics
Gaiak:
autophosphorylation
cell cycle regulation
cellular checkpoint
CIT
citron
DNA repair
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1734030/full
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