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Phosphosite-specific co-regulation networks of MELK kinase: insights from integrative global phosphoproteomes

Maternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase frequently overexpressed in aggressive cancers, yet the precise mechanisms governing its activation and signaling specificity remain poorly understood. Here, we present the first phosphosite-resolved co-regulation atlas of...

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書誌詳細
主要な著者: Noreen A Khan, Amal Fahma, Althaf Mahin, Athira Perunelly Gopalakrishnan, Prathik Basthikoppa Shivamurthy, Samseera Ummar, Athira C. Rajeev, Rajesh Raju
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2026-06-01
シリーズ:Journal of Genetic Engineering and Biotechnology
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1687157X26000491
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