P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in pluripotent cell competition.
Cell Competition is a process by which neighboring cells compare their fitness. As a result, viable but suboptimal cells are selectively eliminated in the presence of fitter cells. In the early mammalian embryo, epiblast pluripotent cells undergo extensive Cell Competition, which prevents suboptimal...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2024-03-01
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| Serie: | PLoS Genetics |
| Accesso online: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011193&type=printable |
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