Reduced SUMOylation impairs NOTCH3 signaling and cell survival in the pathogenesis of CADASIL
Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary cerebral small vessel disease caused by NOTCH3 mutation. The condition leads to recurrent ischemic strokes, vascular dementia, early-onset and high disability, and its preval...
I tiakina i:
| Ngā kaituhi matua: | , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2025-12-01
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| Rangatū: | Cell Communication and Signaling |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s12964-025-02556-7 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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