Integrated bulk and single-cell transcriptomic analyses identify transcriptome-defined groups and EGFR-associated microenvironmental programs in glioma

Abstract Background Glioma exhibits significant molecular heterogeneity, necessitating improved understanding of molecular subtypes for personalized treatment strategies. Methods This study integrated bulk RNA sequencing (GSE35169) to derive transcriptome-defined groups and single-cell RNA sequencin...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Yuanhan Wang, Long Li, Xing Hu, Longhu Han, Yihan Zhang, Zhisen Zhou, Wei Liu, Song Yang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Springer 2026-05-01
Rangatū:	Discover Oncology
Ngā marau:	Glioma Molecular subtypes Single-cell RNA sequencing EGFR Tumor microenvironment
Urunga tuihono:	https://doi.org/10.1007/s12672-026-05138-2
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!