Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes

In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). Dyslipidemia is associated with both excessive deposition of triacylglycerol (TAG) in lipid droplets (LDs) and lipotoxicity. Yet, it is unclear how these two effects correlate with each o...

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Detalhes bibliográficos

Principais autores:	Albert Pérez-Martí, Suresh Ramakrishnan, Jiayi Li, Aurelien Dugourd, Martijn R Molenaar, Luigi R De La Motte, Kelli Grand, Anis Mansouri, Mélanie Parisot, Soeren S Lienkamp, Julio Saez-Rodriguez, Matias Simons
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2022-05-01
coleção:	eLife
Assuntos:	diabetic nephropathy proximal tubules lipotoxicity ER stress membrane order lipid bilayer stress
Acesso em linha:	https://elifesciences.org/articles/74391
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