NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension
Abstract Background Endothelial-to-mesenchymal transition (EndMT) in endothelial dysfunction exacerbates hypertension. However, the regulatory mechanisms underlying EndMT in hypertension are yet to be elucidated. Methods The N-acetyltransferase 10 (NAT10) and N4-acetylcytidine (ac4C) levels were det...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2025-11-01
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| Seria: | Molecular Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s10020-025-01321-3 |
| Etykiety: |
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