NAT10 induces N4-acetylcytidine modification of AdipoR1-mediated mitochondrial biogenesis against endothelial-to-mesenchymal transition in hypertension
Abstract Background Endothelial-to-mesenchymal transition (EndMT) in endothelial dysfunction exacerbates hypertension. However, the regulatory mechanisms underlying EndMT in hypertension are yet to be elucidated. Methods The N-acetyltransferase 10 (NAT10) and N4-acetylcytidine (ac4C) levels were det...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2025-11-01
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| Series: | Molecular Medicine |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s10020-025-01321-3 |
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