QcrC is a potential target for antibody therapy and vaccination to control Campylobacter jejuni infection by suppressing its energy metabolism

IntroductionCampylobacter spp. are a public health concern, yet there is still no effective vaccine or medicine available.MethodsHere, we developed a Campylobacter jejuni-specific antibody and found that it targeted a menaquinol cytochrome c reductase complex QcrC.ResultsThe antibody was specificall...

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Autori principali:	Koji Hosomi, Noritoshi Hatanaka, Atsushi Hinenoya, Jun Adachi, Yoko Tojima, Mari Furuta, Keita Uchiyama, Makiko Morita, Takahiro Nagatake, Azusa Saika, Soichiro Kawai, Ken Yoshii, Saki Kondo, Shinji Yamasaki, Jun Kunisawa
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-07-01
Serie:	Frontiers in Microbiology
Soggetti:	enteric infectious disease Campylobacter inflammation bacterial metabolism cytochrome vaccine
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1415893/full
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