Adjuvant Activity of Synthetic Lipid A of <i>Alcaligenes</i>, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

<i>Alcaligenes</i> spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that <i>Alcaligenes</i>-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without excessive inflammation. Lipid A is one o...

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Detalhes bibliográficos

Principais autores:	Yunru Wang, Koji Hosomi, Atsushi Shimoyama, Ken Yoshii, Haruki Yamaura, Takahiro Nagatake, Tomomi Nishino, Hiroshi Kiyono, Koichi Fukase, Jun Kunisawa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-07-01
coleção:	Vaccines
Assuntos:	<i>Alcaligenes faecalis</i> Th17 lipid A
Acesso em linha:	https://www.mdpi.com/2076-393X/8/3/395
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