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Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality

Abstract Background Investigation of basic chronic inflammatory mechanisms and development of new therapeutics targeting the respiratory tract requires appropriate testing systems, including those to monitor long- persistence. Human precision-cut lung slices (PCLS) have been demonstrated to mimic th...

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Autors principals: Vanessa Neuhaus, Dirk Schaudien, Tatiana Golovina, Ulla-Angela Temann, Carolann Thompson, Torsten Lippmann, Claus Bersch, Olaf Pfennig, Danny Jonigk, Peter Braubach, Hans-Gerd Fieguth, Gregor Warnecke, Vidadi Yusibov, Katherina Sewald, Armin Braun
Format: Artigo
Idioma:Inglês
Publicat: BMC 2017-05-01
Col·lecció:Journal of Occupational Medicine and Toxicology
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Accés en línia:http://link.springer.com/article/10.1186/s12995-017-0158-5
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