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IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.

BACKGROUND:Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modulatio...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Barbara Salani, Mario Passalacqua, Sara Maffioli, Lucia Briatore, Meriem Hamoudane, Paola Contini, Renzo Cordera, Davide Maggi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2010-11-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC2994771?pdf=render
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