IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.
BACKGROUND:Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modulatio...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2010-11-01
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| Serie: | PLoS ONE |
| Accesso online: | http://europepmc.org/articles/PMC2994771?pdf=render |
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