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UNC-10/SYD-2 links kinesin-3 to RAB-3-containing vesicles in the absence of the motor's PH domain

Kinesin-3 KIF1A (UNC-104 in C. elegans) is the major axonal transporter of synaptic vesicles and mutations in this molecular motor are linked to KIF1A-associated neurological disorders (KAND), encompassing Charcot-Marie-Tooth disease, amyotrophic lateral sclerosis and hereditary spastic paraplegia....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Odvogmed Bayansan, Prerana Bhan, Chien-Yu Chang, Syed Nooruzuha Barmaver, Che-Piao Shen, Oliver Ingvar Wagner
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2025-01-01
Cyfres:Neurobiology of Disease
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S0969996124003681
Tagiau: Ychwanegu Tag
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