Increasing in vivo drug exposure levels of compound WX-081 (sudapyridine) when used in combination with clofazimine or clarithromycin
ABSTRACT To examine the in vivo distribution of WX-081 alone or in combination with clarithromycin (Clr) or clofazimine (CFZ) in rats infected with Mycobacterium abscessus and evaluate the effects of the interactions of WX-081 with Clr and CFZ on its tissue distribution, the concentrations of WX-081...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2026-04-01
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| Serie: | Microbiology Spectrum |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/spectrum.01555-25 |
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