Genome-Wide Analysis of Serial Passage of the Infectious Bronchitis Virus Reveals Evolutionary Dynamics Underlying Attenuation and Immunogenicity

<b>Background/Objectives</b>: Serial passage in embryonated eggs is widely used to attenuate the infectious bronchitis virus (IBV) for vaccine production; however, the evolutionary processes underlying attenuation and immunogenicity remain incompletely understood. Here, we analyzed genome-wide viral...

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Ngā kaituhi matua:	Joaquín Williman, Gonzalo Tomas, Ariel Vagnozzi, Claudia Techera, Sebastián Brambillasca, Ruben Pérez, Ana Marandino
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2026-05-01
Rangatū:	Vaccines
Ngā marau:	IBV serial passage attenuation Spike protein viral evolution quasispecies
Urunga tuihono:	https://www.mdpi.com/2076-393X/14/6/467
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!