Immunological effects of CD19.CAR-T cell therapy in systemic sclerosis: an extended case study

Abstract Objective The high potential of CD19.CAR-T cells to treat autoimmune diseases such as Systemic Sclerosis (SSc) supposedly relies on the disappearance of autoantibodies. Here we investigated effects of CAR-T cells on the innate immune system which is an important contributor to pathology in...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Maren Claus, Merle Freitag, Meike Ewald, Lea Rodon, Franca Deicher, Carsten Watzl, Philipp Kolb, Hanns-Martin Lorenz, Michael Schmitt, Wolfgang Merkt
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2024-12-01
Cyfres:	Arthritis Research & Therapy
Pynciau:	Systemic sclerosis Pulmonary fibrosis CAR-T cell therapy NK cells NKG2A Fcγ receptor
Mynediad Ar-lein:	https://doi.org/10.1186/s13075-024-03451-1
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!