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A "trained immunity" inducer-adjuvanted nanovaccine reverses the growth of established tumors in mice

Abstract Innate immune cells are critical in antitumor immune surveillance and the development of antitumor adaptive cellular immunity. Trained innate immune cells demonstrate immune memory-like characteristics, producing more vigorous immune responses to secondary homologous or heterologous stimuli...

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Principais autores: Duo Li, Weiran Li, Peng Zheng, Ying Yang, Qingwen Liu, Yongmao Hu, Jinrong He, Qiong Long, Yanbing Ma
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-03-01
Serier:Journal of Nanobiotechnology
Fag:
Nanovaccine
Trained immunity
MDP
β-glucan
Tumor
Online adgang:https://doi.org/10.1186/s12951-023-01832-3
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