Epstein-Barr Nuclear Antigen 1 modulates replication of <it>oriP</it>-plasmids by impeding replication and transcription fork migration through the family of repeats
<p>Abstract</p> <p>Background</p> <p>Epstein-Barr virus is replicated once per cell-cycle, and partitioned equally in latently infected cells. Both these processes require a single viral <it>cis-</it>element, termed <it>oriP</it>, and a single viral protein, EBNA1. EBNA1 binds two clusters of bindin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMC
2009-03-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/6/1/29 |
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