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Bacterial Lectin FimH and Its Aggregation Hot-Spots: An Alternative Strategy against Uropathogenic <i>Escherichia coli</i>

Type I fimbriae are the main adhesive organelles of uropathogenic <i>Escherichia coli</i> (UPEC), consisting of four different subunits. Their component with the most important role in establishing bacterial infections is the FimH adhesin located at the fimbrial tip. This two-domain protein mediates...

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Principais autores: Georgia I. Nasi, Konstantina I. Georgakopoulou, Marilena K. Theodoropoulou, Nikos C. Papandreou, Evangelia D. Chrysina, Paraskevi L. Tsiolaki, Vassiliki A. Iconomidou
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Pharmaceutics
Fag:
FimH
lectin
type I fimbriae
aggregation-prone regions
prediction
UTIs
Online adgang:https://www.mdpi.com/1999-4923/15/3/1018
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