Immunogenicity of neoantigens from hepatocellular carcinoma patients treated with a combined radioimmunotherapy

In some cancers, patients responding to immune checkpoint inhibitors (ICI) usually harbor tumors with a higher tumor mutational burden and increased lymphocyte infiltration targeting mutation-derived neoantigens (neoAgs). In the NASIR-HCC trial, patients with hepatocellular carcinoma (HCC) received...

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Autori principali:	Belén Aparicio, Leyre Silva, Marta Ruiz, Diana Llópiz, David Repáraz, Patrick Theunissen, Ibon Tamayo, Josune Egea, Ana Igea, Cristian Smerdou, Maria Peñas, Cristina Perpiñá, Ana Matilla, María Varela, Maria Reig, Manuel de la Torre-Alaez, Josepmaria Argemí, Bruno Sangro, Sandra Hervás-Stubbs, Pablo Sarobe
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2026-12-01
Serie:	OncoImmunology
Soggetti:	Hepatocellular carcinoma neoantigens immunotherapy polyepitopic vaccines HLA transgenic mice
Accesso online:	https://www.tandfonline.com/doi/10.1080/2162402X.2026.2645280
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