Metabolomic Profiling and Mechanotransduction of Single Chondrocytes Encapsulated in Alginate Microgels

Articular cartilage is comprised of two main components, the extracellular matrix (ECM) and the pericellular matrix (PCM). The PCM helps to protect chondrocytes in the cartilage from mechanical loads, but in patients with osteoarthritis, the PCM is weakened, resulting in increased chondrocyte stress...

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Bibliografski detalji

Glavni autori:	Jacob P. Fredrikson, Priyanka P. Brahmachary, Ayten E. Erdoğan, Zachary K. Archambault, James N. Wilking, Ronald K. June, Connie B. Chang
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-03-01
Serija:	Cells
Teme:	chondrocytes microgels microfluidics mechanotransduction osteoarthritis pericellular matrix
Online pristup:	https://www.mdpi.com/2073-4409/11/5/900
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