Pyroptosis leads to loss of centrosomal integrity in macrophages
Abstract NLRP3 forms a multiprotein inflammasome complex to initiate the inflammatory response when macrophages sense infection or tissue damage, which leads to caspase-1 activation, maturation and release of the inflammatory cytokines interleukin-1β (IL-1β) and IL-18 and Gasdermin-D (GSDMD) mediate...
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| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2024-08-01
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| Reeks: | Cell Death Discovery |
| Online toegang: | https://doi.org/10.1038/s41420-024-02093-1 |
| Tags: |
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