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Assessment of the expression pattern of HER2 and its correlation with HER2-targeting antibody-drug conjugate therapy in urothelial cancer

Background: Human epidermal growth factor receptor 2 (HER2) overexpression is related to anti-HER2 therapy in many tumors. RC48- antibody-drug conjugate (ADC) has shown promising efficacy in patients with HER2-positive locally advanced or metastatic urothelial carcinoma (UC). The characteristic expr...

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Asıl Yazarlar: Huizi Lei, Yun Ling, Pei Yuan, Xieqiao Yan, Lin Wang, Yanxia Shi, Xin Yao, Hong Luo, Benkang Shi, Jiyan Liu, Zhisong He, Guohua Yu, Weiqing Han, Changlu Hu, Zhihong Chi, Chuanliang Cui, Lu Si, Jianmin Fang, Jun Guo, Xinan Sheng, Aiping Zhou, Jianming Ying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2023-06-01
Seri Bilgileri:Journal of the National Cancer Center
Konular:
Urothelial carcinoma
Anti-HER2-ADC
HER2
Fluorescence in situ hybridization
Immunohistochemistry
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2667005423000182
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