Localization of the PelC and PelE effectors to the Legionella-containing vacuole through host-mediated prenylation and their role in intracellular proliferation
ABSTRACT Legionella pneumophila is an intracellular pathogen that replicates in macrophage and protozoan hosts within an endoplasmic reticulum (ER)-derived phagosome that evades the endosomal-lysosomal degradation pathway. The Dot/Icm Type IV Secretion System (T4SS) of L. pneumophila injects ~368 ef...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2026-04-01
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| Col·lecció: | Infection and Immunity |
| Matèries: | |
| Accés en línia: | https://journals.asm.org/doi/10.1128/iai.00605-25 |
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