Novel Sulfonamide-Based Analogs of Metformin Exert Promising Anti-Coagulant Effects without Compromising Glucose-Lowering Activity

Metformin, one of the most frequently prescribed oral anti-diabetic drugs, is characterized by multidirectional activity, including lipid lowering, cardio-protective and anti-inflammatory properties. This study presents synthesis and stability studies of 10 novel sulfonamide-based derivatives of met...

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Hlavní autoři:	Magdalena Markowicz-Piasecka, Adrianna Sadkowska, Joanna Sikora, Marlena Broncel, Kristiina M. Huttunen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-10-01
Edice:	Pharmaceuticals
Témata:	hemostasis coagulation biguanide metformin endothelium
On-line přístup:	https://www.mdpi.com/1424-8247/13/10/323
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