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Novel Sulfonamide-Based Analogs of Metformin Exert Promising Anti-Coagulant Effects without Compromising Glucose-Lowering Activity

Metformin, one of the most frequently prescribed oral anti-diabetic drugs, is characterized by multidirectional activity, including lipid lowering, cardio-protective and anti-inflammatory properties. This study presents synthesis and stability studies of 10 novel sulfonamide-based derivatives of met...

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Principais autores: Magdalena Markowicz-Piasecka, Adrianna Sadkowska, Joanna Sikora, Marlena Broncel, Kristiina M. Huttunen
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2020-10-01
סדרה:Pharmaceuticals
נושאים:
hemostasis
coagulation
biguanide
metformin
endothelium
גישה מקוונת:https://www.mdpi.com/1424-8247/13/10/323
תגים: הוספת תג
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