The intersection of homologous recombination (HR) and mismatch repair (MMR) pathways in DNA repair-defective tumors

Abstract Homologous recombination (HR) and mismatch repair (MMR) defects are driver mutational imprints and actionable biomarkers in DNA repair-defective tumors. Although usually thought as mutually exclusive pathways, recent preclinical and clinical research provide preliminary evidence of a functi...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Lorena Incorvaia, Tancredi Didier Bazan Russo, Valerio Gristina, Alessandro Perez, Chiara Brando, Clarissa Mujacic, Emilia Di Giovanni, Marco Bono, Silvia Contino, Carla Ferrante Bannera, Maria Concetta Vitale, Andrea Gottardo, Marta Peri, Antonio Galvano, Daniele Fanale, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2024-09-01
Rangatū:	npj Precision Oncology
Urunga tuihono:	https://doi.org/10.1038/s41698-024-00672-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!