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Antibody in Lymphocyte Supernatant (ALS) responses after oral vaccination with live Shigella sonnei vaccine candidates WRSs2 and WRSs3 and correlation with serum antibodies, ASCs, fecal IgA and shedding.

The levels of antigen-specific Antibodies in Lymphocyte Supernatant (ALS) using an ELISA are being used to evaluate mucosal immune responses as an alternate to measuring the number of Antibody Secreting Cells (ASCs) using an ELISpot assay. A recently completed trial of two novel S. sonnei live oral...

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主要な著者: Malabi M Venkatesan, Cassandra Ballou, Shoshana Barnoy, Monica McNeal, Jill El-Khorazaty, Robert Frenck, Shahida Baqar
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2021-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0259361&type=printable
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