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Antibody in Lymphocyte Supernatant (ALS) responses after oral vaccination with live Shigella sonnei vaccine candidates WRSs2 and WRSs3 and correlation with serum antibodies, ASCs, fecal IgA and shedding.

The levels of antigen-specific Antibodies in Lymphocyte Supernatant (ALS) using an ELISA are being used to evaluate mucosal immune responses as an alternate to measuring the number of Antibody Secreting Cells (ASCs) using an ELISpot assay. A recently completed trial of two novel S. sonnei live oral...

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Бібліографічні деталі
Автори: Malabi M Venkatesan, Cassandra Ballou, Shoshana Barnoy, Monica McNeal, Jill El-Khorazaty, Robert Frenck, Shahida Baqar
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2021-01-01
Серія:PLoS ONE
Онлайн доступ:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0259361&type=printable
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