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Targeting vascular normalization: a promising strategy to improve immune–vascular crosstalk in cancer immunotherapy

Blood vessels are a key target for cancer therapy. Compared with the healthy vasculature, tumor blood vessels are extremely immature, highly permeable, and deficient in pericytes. The aberrantly vascularized tumor microenvironment is characterized by hypoxia, low pH, high interstitial pressure, and...

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Principais autores: Cheng Qian, Chaoqun Liu, Weiwei Liu, Rui Zhou, Liang Zhao
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2023-12-01
Serija:Frontiers in Immunology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291530/full
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