S100A9 and HMGB1 orchestrate MDSC-mediated immunosuppression in melanoma through TLR4 signaling

Background Immunotherapies for malignant melanoma are challenged by the resistance developed in a significant proportion of patients. Myeloid-derived suppressor cells (MDSC), with their ability to inhibit antitumor T-cell responses, are a major contributor to immunosuppression and resistance to immu...

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Detalhes bibliográficos

Principais autores:	Adelheid Cerwenka, Jochen Utikal, Viktor Umansky, Carolina De La Torre, Feyza Gül Özbay Kurt, Beatrice-Ana Cicortas, Bianca M Balzasch, Volker Ast, Ece Tavukcuoglu, Cagla Ak, Sebastian A Wohlfeil
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 2024-09-01
Colecção:	Journal for ImmunoTherapy of Cancer
Acesso em linha:	https://jitc.bmj.com/content/12/9/e009552.full
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