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Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators

Summary: The immune system is highly diverse, but characterization of its genetic architecture has lagged behind the vast progress made by genome-wide association studies (GWASs) of emergent diseases. Our GWAS for 54 functionally relevant phenotypes of the adaptive immune system in 489 healthy indiv...

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Principais autores: Vasiliki Lagou, Josselyn E. Garcia-Perez, Ide Smets, Lies Van Horebeek, Marijne Vandebergh, Liye Chen, Klara Mallants, Teresa Prezzemolo, Kelly Hilven, Stephanie Humblet-Baron, Matthieu Moisse, Philip Van Damme, Guy Boeckxstaens, Paul Bowness, Bénédicte Dubois, James Dooley, Adrian Liston, An Goris
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018-10-01
coleção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124718314931
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