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Modifications of the BAFF/BAFF-Receptor Axis in Patients With Pemphigus Treated With Rituximab Versus Standard Corticosteroid Regimen

The efficacy of the B-cell-depleting agent rituximab has been reported in immune diseases but relapses are frequent, suggesting the need for repeated infusions. The B-cell activating factor (BAFF) is an important factor for B cell survival, class switch recombination and selection of autoreactive B...

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Principais autores: Vivien Hébert, Maud Maho-Vaillant, Marie-Laure Golinski, Marie Petit, Gaëtan Riou, Olivier Boyer, Philippe Musette, Sébastien Calbo, Pascal Joly
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-05-01
coleção:Frontiers in Immunology
Assuntos:
Pemphigus
BAFF - B-cell activating factor
BAFF-receptor
rituximab
Corticosteroïd
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.666022/full
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