Mechanisms of telomere loss and their consequences for chromosome instability
The ends of chromosomes in mammals, called telomeres, are composed of a 6 base pair repeat sequence, TTAGGG, which is added on by the enzyme telomerase. In combination with a protein complex called shelterin, these telomeric repeat sequences form a cap that protects the ends of chromosomes. Due to...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2012-10-01
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| Seri Bilgileri: | Frontiers in Oncology |
| Konular: | |
| Online Erişim: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00135/full |
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