Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1

Abstract TNF is a central actor during inflammation and a well‐recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF‐induced shock, displays weak expression of TNF receptor 1 protein (TNFR1) but normal mRNA ex...

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主要な著者:	Leen Puimège, Filip Van Hauwermeiren, Sophie Steeland, Sara Van Ryckeghem, Jolien Vandewalle, Sofie Lodens, Lien Dejager, Sofie Vandevyver, Jan Staelens, Steven Timmermans, Roosmarijn E Vandenbroucke, Claude Libert
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer Nature 2015-05-01
シリーズ:	EMBO Molecular Medicine
主題:	glucocorticoids miRs receptor regulation sepsis TNF
オンライン･アクセス:	https://doi.org/10.15252/emmm.201405010
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