Key determinants of the dual clamp/activator function of Complexin
Complexin determines magnitude and kinetics of synchronized secretion, but the underlying molecular mechanisms remained unclear. Here, we show that the hydrophobic face of the amphipathic helix at the C-terminus of Complexin II (CpxII, amino acids 115–134) binds to fusion-promoting SNARE proteins, p...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications Ltd
2024-11-01
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| Edice: | eLife |
| Témata: | |
| On-line přístup: | https://elifesciences.org/articles/92438 |
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