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Anti-hypertensive effect of a novel angiotensin II receptor neprilysin inhibitor (ARNi) -S086 in DSS rat model

IntroductionAngiotensin receptor-neprilysin inhibitor (ARNi), comprised of an angiotensin receptor blocker (ARB) and a neprilysin inhibitor (NEPi), has established itself as a safe and effective intervention for hypertension. S086 is a novel ARNi cocrystal developed by Salubris for the treatment of...

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Principais autores: Jingchao Sun, Ying Xiao, Wenjie Xu, Wei Xing, Frank Du, Maozhi Tian, Danqi Xu, Yihua Ren, Xin Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-02-01
coleção:Frontiers in Cardiovascular Medicine
Assuntos:
angiotensin receptor-NEP inhibitor (ARNi)
hypertension
neprilysin inhibitor
angiotensin receptor blocker (ARB)
natriuresis
diuresis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1348897/full
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