Anti-hypertensive effect of a novel angiotensin II receptor neprilysin inhibitor (ARNi) -S086 in DSS rat model

IntroductionAngiotensin receptor-neprilysin inhibitor (ARNi), comprised of an angiotensin receptor blocker (ARB) and a neprilysin inhibitor (NEPi), has established itself as a safe and effective intervention for hypertension. S086 is a novel ARNi cocrystal developed by Salubris for the treatment of...

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Autors principals:	Jingchao Sun, Ying Xiao, Wenjie Xu, Wei Xing, Frank Du, Maozhi Tian, Danqi Xu, Yihua Ren, Xin Fang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-02-01
Col·lecció:	Frontiers in Cardiovascular Medicine
Matèries:	angiotensin receptor-NEP inhibitor (ARNi) hypertension neprilysin inhibitor angiotensin receptor blocker (ARB) natriuresis diuresis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcvm.2024.1348897/full
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