Role of the endocannabinoid system in fragile X syndrome: potential mechanisms for benefit from cannabidiol treatment

Abstract Multiple lines of evidence suggest a central role for the endocannabinoid system (ECS) in the neuronal development and cognitive function and in the pathogenesis of fragile X syndrome (FXS). This review describes the ECS, its role in the central nervous system, how it is dysregulated in FXS...

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Autores principales:	Joseph M. Palumbo, Brian F. Thomas, Dejan Budimirovic, Steven Siegel, Flora Tassone, Randi Hagerman, Christopher Faulk, Stephen O’Quinn, Terri Sebree
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-01-01
Colección:	Journal of Neurodevelopmental Disorders
Materias:	Fragile X syndrome Endocannabinoid system Cannabinoid receptors Cannabidiol
Acceso en línea:	https://doi.org/10.1186/s11689-023-09475-z
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