Electrophysiological classification of CACNA1G gene variants associated with neurodevelopmental and neurological disorders

This study highlights the complementarity of automated patch-clamp (APC) and manual patch-clamp (MPC) approaches to describe the electrophysiological properties of eighteen Cav3.1 calcium channel variants associated with various neurological conditions. Current density was measured efficiently for a...

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Autori principali:	Amaël Davakan, Leos Cmarko, Barbara Ribeiro Oliveira-Mendes, Claire Bernat, Najlae Boulali, Jérôme Montnach, Stephanie E. Vallee, Mary B. Dinulos, Lydie Burglen, Vincent Cantagrel, Norbert Weiss, Sophie Nicole, Arnaud Monteil, Michel De Waard, Philippe Lory
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-10-01
Serie:	Frontiers in Pharmacology
Soggetti:	calcium channel SCA42ND electrophysiology automated patch-clamp Cav3.1
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1613072/full
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