Identification of Novel Arachidonic Acid 15-Lipoxygenase Inhibitors Based on the Bayesian Classifier Model and Computer-Aided High-Throughput Virtual Screening

Ferroptosis is an iron-dependent lipid peroxidative form of cell death that is distinct from apoptosis and necrosis. ALOX15, also known as arachidonic acid 15-lipoxygenase, promotes ferroptosis by converting intracellular unsaturated lipids into oxidized lipid intermediates and is an important ferro...

Descripció completa

Dades bibliogràfiques

Autors principals:	Yinglin Liao, Peng Cao, Lianxiang Luo
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-11-01
Col·lecció:	Pharmaceuticals
Matèries:	ferroptosis ALOX15 homology modeling machine learning virtual screening molecular dynamic simulation
Accés en línia:	https://www.mdpi.com/1424-8247/15/11/1440
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!