Lachnospiraceae-bacterium alleviates ischemia-reperfusion injury in steatotic donor liver by inhibiting ferroptosis via the Foxo3-Alox15 signaling pathway

Ischemia-reperfusion injury (IRI) is a major obstacle in liver transplantation, especially with steatotic donor livers. Dysbiosis of the gut microbiota has been implicated in modulating IRI, and Lachnospiraceae plays a pivotal role in regulating host inflammatory and immune responses, but its specif...

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Autori principali:	Shenghe Deng, Huan Cao, Tongxi Li, Xueling Wang, Junpeng Meng, Teng Zeng, Di Zhang, Shuhua Zhang, Guoliang Wang, Ran Liu, Tianhao Zou, Mao Cai, Ren Lang, Di Lu, Jinyang Gu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2025-12-01
Serie:	Gut Microbes
Soggetti:	Lachnospiraceae-bacterium steatotic donor livers ferroptosis liver transplantation Alox15
Accesso online:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2460543
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