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Using the Cyclotide Scaffold for Targeting Biomolecular Interactions in Drug Development

This review provides an overview of the properties of cyclotides and their potential for developing novel peptide-based therapeutics. The selective disruption of protein–protein interactions remains challenging, as the interacting surfaces are relatively large and flat. However, highly constrained p...

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Principais autores: Binu Jacob, Alicia Vogelaar, Enrique Cadenas, Julio A. Camarero
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-09-01
Colecção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/27/19/6430
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