Functional characterization of genetic variants affecting the intracellular domains of ATP-binding cassette transporter A1 (ABCA1)

The ATP-binding cassette transporter A1 (ABCA1) effluxes cellular cholesterol and phospholipids to extracellular acceptors, mainly apolipoprotein A1, generating high-density lipoprotein (HDL) particles. This is the first step in the anti-atherosclerotic process of transporting excess cholesterol fro...

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Detalhes bibliográficos

Principais autores:	Marianne Teigen, Åsa Schawlann Ølnes, Katrine Bjune, Martin Prøven Bogsrud, Thea Bismo Strøm
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-08-01
coleção:	Journal of Lipid Research
Assuntos:	HEK293 cells Tangier disease cholesterol efflux HDL lipid metabolism lipoproteins
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227525001154
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