Multiple dysfunctions of two apolipoprotein A-I variants, apoA-I(R160L)Oslo and apoA-I(P165R), that are associated with hypoalphalipoproteinemia in heterozygous carriers

ApoA-I(R160L)Oslo and apoA-I(P165R) are naturally occurring apolipoprotein (apo) A-I variants that are associated with low HDL-cholesterol in heterozygous carriers. We characterized the capacity of these variants to bind lipid, to activate lecithin:cholesterol acyltransferase (LCAT), and to promote...

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主要な著者:	Ulrike Daum, Trond P. Leren, Claus Langer, Ali Chirazi, Paul Cullen, P. Haydn Pritchard, Gerd Assmann, Arnold von Eckardstein
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 1999-03-01
シリーズ:	Journal of Lipid Research
主題:	familial hypoalphalipoproteinemia apoA-I variants cholesterol efflux LCAT reverse cholesterol transport
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S0022227520324536
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