Structures of vesicular stomatitis virus glycoprotein G alone and bound to a neutralizing antibody.

VSV G mediates viral entry via endocytosis. In the endosome, G undergoes a pH-dependent conformational change from pre- to post-fusion state, catalyzing membrane fusion. No complete structure of G has been reported so far. We present cryo-EM structures of G, isolated from virions using detergent, al...

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Hlavní autoři:	Marie Minoves, Malika Ouldali, Laura Belot, Stéphane Roche, Sarah Johari, Magali Noiray, Eleftherios Zarkadas, Guy Schoehn, Yves Gaudin, Aurélie A Albertini
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2025-10-01
Edice:	PLoS Pathogens
On-line přístup:	https://doi.org/10.1371/journal.ppat.1013589
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