Structures of vesicular stomatitis virus glycoprotein G alone and bound to a neutralizing antibody.
VSV G mediates viral entry via endocytosis. In the endosome, G undergoes a pH-dependent conformational change from pre- to post-fusion state, catalyzing membrane fusion. No complete structure of G has been reported so far. We present cryo-EM structures of G, isolated from virions using detergent, al...
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| Principais autores: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2025-10-01
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| 叢編: | PLoS Pathogens |
| 在線閱讀: | https://doi.org/10.1371/journal.ppat.1013589 |
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