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Persistence of an intact HIV reservoir in phenotypically naive T cells

Despite the efficacy of antiretroviral therapy (ART), HIV persists in a latent form and remains a hurdle to eradication. CD4+ T lymphocytes harbor the majority of the HIV reservoir, but the role of individual subsets remains unclear. CD4+ T cells were sorted into central, transitional, effector memo...

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Bibliografische Detailangaben
Hauptverfasser: Emmanuele Venanzi Rullo, Marilia Rita Pinzone, LaMont Cannon, Sam Weissman, Manuela Ceccarelli, Ryan Zurakowski, Giuseppe Nunnari, Una O’Doherty
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical investigation 2020-10-01
Schriftenreihe:JCI Insight
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Online-Zugang:https://doi.org/10.1172/jci.insight.133157
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