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The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease

Abstract A CAG repeat sequence in the ATXN2 gene encodes a polyglutamine (polyQ) tract within the ataxin-2 (ATXN2) protein, showcasing a complex landscape of functions that have been progressively unveiled over recent decades. Despite significant progresses in the field, a comprehensive overview of...

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Päätekijät: Rafael G. Costa, André Conceição, Carlos A. Matos, Clévio Nóbrega
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2024-06-01
Sarja:Cell Death and Disease
Linkit:https://doi.org/10.1038/s41419-024-06812-5
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